Basic Information
| ID | DRAMP02056 |
| Sequence | GLLDTFKNMAINAAHGAGVSVLNALSCKLKKTC |
| Length | 33 |
| Name | Brevinin-2-OA3 (Frogs, amphibians, animals) |
| Source | Odorrana andersonii (Chinese odorous frog) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
| Pathogen | Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=6.3 µg/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=12.6 µg/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=6.3 µg/ml).##Yeast: Candida albicans (MIC=3.2 µg/ml). |
| Hemolytic Activity | [Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 μg/mL. |
| Cytotoxicity | No cytotoxicity information found |
| N-terminal Modification | Free |
| C-terminal Modification | Cyclization (Cys27 and Cys33) |
| Linear/Cyclic/Branched | Cyclic |
| Uniprot |
|
| PDB |
|
| 3D View | |
|---|
| PDB Download | Download PDB Predicted by Alphafold2 |
|---|
| PubMed ID | 22029824 |
|---|