Basic Information

IDDRAMP01994
SequenceSLLDTFKNLAVNAAKSAGVSVLNALSCKISRTC
Length33
NameBrevinin-2ISa (Frogs, amphibians, animals)
SourceOdorrana ishikawae (Endangered frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacterium: Escherichia coli (MIC=50 µM);##Gram-positive bacteria: Staphylococcus aureus (MIC=12.5 µM), S. aureus (MRSA) (MIC=100 µM), Bacillus subtilis (MIC=12.5 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID21193000

Physicochemical Properties

Residues33
SequenceSLLDTFKNLAVNAAKSAGVSVLNALSCKISRTC
Molecular Weight3395.946
Grand Average of Hydropathy0.512
Isoelectric Point9.384
Charge at pH 7.42.197
Secondary StructureHelix: 0.303, Turn: 0.273, Sheet: 0.303
Instability Index17.47
Aromaticity0.03

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