Basic Information

IDDRAMP01374
SequenceGFLDTFKNLALNAAKSAGVSVLNSLSCKLFKTC
Length33
NameOdorranain-D1 (OdD1; Frogs, amphibians, animals)
SourceOdorrana grahami (Yunnanfu frog) (Rana grahami)
ActivityAntimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-
Pathogen[Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC=16.32 μg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=8.16 μg/ml), Bacillus subtilis (MIC=8.16 μg/ml).##Yeast: Candida albicans (MIC=4.08 μg/ml).
Hemolytic Activity[Ref:17272268]Non-hemolytic activity against rabbit red blood cells
Cytotoxicity[Ref.17272268]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization(Cys27 and Cys33)
Linear/Cyclic/BranchedCyclic
Uniprot A6MBK7
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17272268

Physicochemical Properties

Residues33
SequenceGFLDTFKNLALNAAKSAGVSVLNSLSCKLFKTC
Molecular Weight3462.046
Grand Average of Hydropathy0.509
Isoelectric Point9.308
Charge at pH 7.42.499
Secondary StructureHelix: 0.333, Turn: 0.273, Sheet: 0.303
Instability Index7.079
Aromaticity0.091

Similar Structure Search

Candidates based on structure

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