Basic Information
| ID | DRAMP01986 |
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| Sequence | SLLGTVKDLLIGAGKSAAQSVLKGLSCKLSKDC |
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| Length | 33 |
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| Name | Brevinin-2HS2 (Frogs, amphibians, animals) |
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| Source | Huia schmackeri (Chinese piebald odorous frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | Gram-positive bacteria: Staphylococcus aureus ATCC2592 (MIC=19 µM), Bacillus licheniformis X39 (MIC=39 µM), Rhodococcus rhodochrous X15 (MIC=9.5 µM);##Gram-negative bacterium: Psychrobacter faecalis X29 (MIC=9.5 µM).##Fungi: Slime mould 090223 (MIC=37.5 µM), Candida albicans ATCC2002 (MIC=19 µM). |
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| Hemolytic Activity | LC50=300µM against human erythrocytes |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys27 and Cys33) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 18423796 |
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