Basic Information

IDDRAMP01995
SequenceSFLTTFKDLAIKAAKSAGQSVLSTLSCKLSNTC
Length33
NameBrevinin-2ISb (Frogs, amphibians, animals)
SourceOdorrana ishikawae (Endangered frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacterium: Escherichia coli (MIC=12.5 µM);##Gram-positive bacteria: Staphylococcus aureus (MIC=6.3 µM), Bacillus subtilis (MIC=25 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID21193000

Physicochemical Properties

Residues33
SequenceSFLTTFKDLAIKAAKSAGQSVLSTLSCKLSNTC
Molecular Weight3434.976
Grand Average of Hydropathy0.345
Isoelectric Point9.303
Charge at pH 7.42.195
Secondary StructureHelix: 0.273, Turn: 0.242, Sheet: 0.273
Instability Index24.358
Aromaticity0.061

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