Basic Information

IDDRAMP01960
SequenceFLPILASLAAKFGPKLFCLVTKKC
Length24
NameBrevinin-1BYa (Frogs, amphibians, animals)
SourceRana boylii (Foothill yellow-legged frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.14531844]Gram-positive bacterium: Staphylococcus aureus(MIC=2 µM);##Gram-negative bacterium: Escherichia coli(MIC=17 µM);##Yeast: Candida albicans(MIC=3 µM)
Hemolytic Activity[Ref.14531844]HC50=4 µM against human erythrocytes
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P84111
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID14531844

Physicochemical Properties

Residues24
SequenceFLPILASLAAKFGPKLFCLVTKKC
Molecular Weight2609.285
Grand Average of Hydropathy1.075
Isoelectric Point9.701
Charge at pH 7.43.498
Secondary StructureHelix: 0.417, Turn: 0.167, Sheet: 0.333
Instability Index26.583
Aromaticity0.125

Similar Structure Search

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