Basic Information

IDDRAMP01961
SequenceFLPILASLAAKLGPKLFCLVTKKC
Length24
NameBrevinin-1BYb (Frogs, amphibians, animals)
SourceRana boylii (Foothill yellow-legged frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.14531844]Gram-positive bacterium: Staphylococcus aureus(MIC=4 µM);##Gram-negative bacterium: Escherichia coli(MIC=16 µM);##Yeast: Candida albicans(MIC=16 µM).
Hemolytic Activity[Ref.14531844]HC50=4 µM against human erythrocytes
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P84112
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID14531844

Physicochemical Properties

Residues24
SequenceFLPILASLAAKLGPKLFCLVTKKC
Molecular Weight2575.269
Grand Average of Hydropathy1.117
Isoelectric Point9.701
Charge at pH 7.43.498
Secondary StructureHelix: 0.417, Turn: 0.167, Sheet: 0.375
Instability Index23.046
Aromaticity0.083

Similar Structure Search

Candidates based on structure

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