Basic Information
| ID | DRAMP02035 |
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| Sequence | FLPILAGLAANILPKVFCSITKKC |
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| Length | 24 |
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| Name | Brevinin-1AUb (Frogs, amphibians, animals) |
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| Source | Rana aurora aurora (Northern red-legged frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.15325526]Gram-negative bacteria: Escherichia coli (MIC=25 µM), Pseudomonas aeruginosa (MIC=25 µM), Enterobacter cloacae (MIC=25 µM), Klebsiella pneumoniae (MIC>50 µM), Proteus mirabilis (MIC>50 µM);##Gram-positive bacteria: Staphylococcus aureus (MIC=3 µM), Staphylococcus epidermidis (MIC=6 µM), Enterococcus faecalis (MIC=6 µM), Streptococcus Group B (MIC=13 µM);##Yeast: Candida albicans (MIC=3 µM). |
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| Hemolytic Activity | [Ref.15325526] HC50=7 μM against human erythrocytes |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys18 and Cys24) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 15325526 |
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