Basic Information

IDDRAMP02231
SequenceFLPFIARLAAKVFPSIICSVTKKC
Length24
NameRanatuerin-4 (Frogs, amphibians, animals)
SourceLithobates catesbeiana (American bullfrog) (Rana catesbeiana)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
Pathogen[Ref.9784389] Gram-positive bacterium: Staphylococcus aureus (MIC=55 µM).
Hemolytic Activity[Ref.9784389] Have no detectable hemolytic activity at aconcentration of 20µg/ml against human red blood cell.
Cytotoxicity[Ref.9784389]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys18 and Cys24)
Linear/Cyclic/BranchedCyclic
Uniprot P82819
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID9784389

Physicochemical Properties

Residues24
SequenceFLPFIARLAAKVFPSIICSVTKKC
Molecular Weight2653.298
Grand Average of Hydropathy1.108
Isoelectric Point9.851
Charge at pH 7.43.501
Secondary StructureHelix: 0.417, Turn: 0.167, Sheet: 0.208
Instability Index34.608
Aromaticity0.125

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.