Basic Information
| ID | DRAMP02001 |
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| Sequence | FLPLIASLAANFVPKIFCKITKKC |
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| Length | 24 |
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| Name | Brevinin-1HN1 (Frogs, amphibians, animals) |
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| Source | Odorrana hainanensis (Hainan odorous frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.22450466]Gram-positive bacteria: Enterococcus faecium 091299 (MIC=19 µM), Enterococcus faecalis 981 (MIC=19 µM), Staphylococcus aureus ATCC2592 (MIC=1.2 µM), Staphylococcus carnosus KHS (MIC=4.8 µM), Bacillus licheniformis X39 (MIC=2.4 µM), Rhodococcus rhodochrous X15 (MIC=1.2 µM);##Gram-negative bacteria: Escherichia coli ATCC25922 (MIC=150 µM), Psychrobacter faecalis X29 (MIC=4.8 µM);##Fungi: Slime mould 090223 (MIC=1.2 µM), Candida albicans ATCC2002 (MIC=2.4 µM). |
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| Hemolytic Activity | [Ref.22450466] LC50=75 µM against human erythrocytes |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys18 and Cys24) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
E7EKC4 |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 22450466 |
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