Basic Information

IDDRAMP01918
SequenceFLPLIAGLAANFLPKIFCAITKKC
Length24
NameBrevinin-1PLb (Frogs, amphibians, animals)
SourceRana palustris (Pickerel frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacterium: Staphylococcus aureus (MIC=9 µM);##Gram-negative bacterium: Escherichia coli(MIC=26 µM).##Yeast: Candida albicans (MIC=6 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot A7WNV3
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17698247, 11087945

Physicochemical Properties

Residues24
SequenceFLPLIAGLAANFLPKIFCAITKKC
Molecular Weight2593.242
Grand Average of Hydropathy1.242
Isoelectric Point9.39
Charge at pH 7.42.501
Secondary StructureHelix: 0.417, Turn: 0.167, Sheet: 0.333
Instability Index15.833
Aromaticity0.125

Similar Structure Search

Candidates based on structure

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