Basic Information

IDDRAMP01919
SequenceFLPVIAGVAAKFLPKIFCAITKKC
Length24
NameBrevinin-1PLc (Frogs, amphibians, animals)
SourceRana palustris (Pickerel frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacterium: Staphylococcus aureus (MIC=4 µM);##Gram-negative bacterium: Escherichia coli(MIC=7 µM).##Yeast: Candida albicans (MIC=8 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot A7WNV4
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17698247, 11087945

Physicochemical Properties

Residues24
SequenceFLPVIAGVAAKFLPKIFCAITKKC
Molecular Weight2579.259
Grand Average of Hydropathy1.258
Isoelectric Point9.701
Charge at pH 7.43.498
Secondary StructureHelix: 0.417, Turn: 0.125, Sheet: 0.250
Instability Index30.121
Aromaticity0.125

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