Basic Information
| ID | DRAMP01940 |
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| Sequence | FLPIIAGVAAKVLPKLFCAITKKC |
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| Length | 24 |
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| Name | Brevinin-1CHa (Frogs, amphibians, animals) |
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| Source | Rana chiricahuensis |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | Gram-negative bacteria: E. coli (MIC=10 µM), K. pneumoniae (MIC=40 µM), P. aeruginosa (MIC=20 µM);##Gram-positive bacterium: S. aureus (MIC=2.5 µM).##Yeast: C. albicans (MIC=2.5 µM).(Ref.2) |
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| Hemolytic Activity | [Ref.21262304] LC50=5 µM against human erythrocytes |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys18 and Cys24) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
A7YJE2 |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 17938991, 21262304 |
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