Basic Information
| ID | DRAMP01891 |
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| Sequence | FLPVIASVAAKVLPKVFCFITKKC |
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| Length | 24 |
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| Name | Brevinin-1VLc (Frogs, amphibians, animals) |
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| Source | Rana vaillanti (Central American frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | Gram-negative bacterium: E. coli (MIC=50 µM);##Gram-positive bacterium: S. aureus (MIC=1.5 µM).##Yeast: C. albicans (MIC=3 µM). |
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| Hemolytic Activity | [Ref.19379837] LC50=7 mM against human erythrocytes |
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| Cytotoxicity | [Ref.19379837] LC50=4mM against HepG2 hepatoma-derived cells |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys18 and Cys24) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 19379837 |
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