Basic Information

IDDRAMP01966
SequenceFLPVIAGVAANFLPKLFCAISKKC
Length24
NameBrevinin-1Ya (Frogs, amphibians, animals)
SourceLithobates yavapaiensis (North America leopard frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.19254736] Gram-positive bacteria : Staphylococcus aureus(MIC=3 μM);##Gram-negative bacteria : Escherichia coli(MIC=50 μM);##Fungi : Candida albicans(MIC=12 μM)
Hemolytic Activity[Ref.19254736] LC50=18 μM against human red blood cells
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19254736

Physicochemical Properties

Residues24
SequenceFLPVIAGVAANFLPKLFCAISKKC
Molecular Weight2551.163
Grand Average of Hydropathy1.242
Isoelectric Point9.39
Charge at pH 7.42.501
Secondary StructureHelix: 0.417, Turn: 0.208, Sheet: 0.292
Instability Index23.858
Aromaticity0.125

Similar Structure Search

Candidates based on structure

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