Basic Information
| ID | DRAMP02081 |
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| Sequence | FLPLLAGLAANFLPKIFCKITRKC |
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| Length | 24 |
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| Name | Brevinin-1E (Frogs, amphibians, animals) |
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| Source | Rana esculenta (Edible frog) (Pelophylax esculentus) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Anti Mammalian Cells |
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| Pathogen | [Ref.8163497] Gram-negative bacteria: Escherichia coliD21 (MIC=1.8 µM), Pseudomonas aeruginosa ATCC15692 (MIC=30.6 µM);##Gram-positive bacteria: Bacillus megaterium Bm11 (MIC=0.4 µM), Staphylococcus aureus Cowan1 (MIC=0.6 µM);##Fungi: Candida albicans (MIC=4.7 µM);##Yeast: Saccharomyces cerevisiae (MIC=3.8 µM). |
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| Hemolytic Activity | [Ref.8163497] LC50=0.5 µM against human red blood cell. |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys18 and Cys24) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
P32412 |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 8508915, 8163497 |
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