Basic Information

IDDRAMP01913
SequenceFLPLLAGLAANFLPKIFCKITKKC
Length24
NameBrevinin-1GRa (Frogs, amphibians, animals)
SourceRana grahami (Asian frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacterium: Escherichia coli (MIC=25 µM);##Gram-positive bacterium: Staphylococcus aureus (MIC=12.5 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys18 and Cys24)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16621155

Physicochemical Properties

Residues24
SequenceFLPLLAGLAANFLPKIFCKITKKC
Molecular Weight2650.337
Grand Average of Hydropathy0.975
Isoelectric Point9.701
Charge at pH 7.43.498
Secondary StructureHelix: 0.417, Turn: 0.167, Sheet: 0.333
Instability Index12.296
Aromaticity0.125

Similar Structure Search

Candidates based on structure

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