| ID | DRAMP02018 |
|---|---|
| Sequence | FLSLALAALPKLFCLIFKKC |
| Length | 20 |
| Name | Brevinin-1DYb (Brevinin-1CDYb; Frogs, amphibians, animals) |
| Source | Rana dybowskii (Dybovsky's frog) (Korean brown frog) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Swiss_Prot Entry P0C5W7]Gram-positive bacterium: Staphylococcus aureus (low activity);##Gram-negative bacterium: Escherichia coli (MIC<15 µM). |
| Hemolytic Activity | [Ref.17688900]LC50<6 μM against human erythrocytes |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | P0C5W7 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 19539775, 17688900 |
Physicochemical Properties
| Residues | 20 |
|---|---|
| Sequence | FLSLALAALPKLFCLIFKKC |
| Molecular Weight | 2239.869 |
| Grand Average of Hydropathy | 1.6 |
| Isoelectric Point | 9.39 |
| Charge at pH 7.4 | 2.501 |
| Secondary Structure | Helix: 0.500, Turn: 0.100, Sheet: 0.450 |
| Instability Index | 17 |
| Aromaticity | 0.15 |