Basic Information

IDDRAMP02026
SequenceLLSLALAALPKLFCLIFKKC
Length20
NameBrevinin-1CDYa (Frogs, amphibians, animals)
SourceRana dybowskii (Dybovsky's frog) (Korean brown frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Swiss_Prot Entry B3VZU0]Gram-positive bacterium: Staphylococcus aureus (MIC=12.5 µM);##Gram-negative bacterium: Escherichia coli (MIC=25 µM)
Hemolytic Activity[Ref.19539775]HC50=125 μM against human red blood cells
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys14 and Cys20)
Linear/Cyclic/BranchedCyclic
Uniprot B3VZU0
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19539775

Physicochemical Properties

Residues20
SequenceLLSLALAALPKLFCLIFKKC
Molecular Weight2205.853
Grand Average of Hydropathy1.65
Isoelectric Point9.39
Charge at pH 7.42.501
Secondary StructureHelix: 0.500, Turn: 0.100, Sheet: 0.500
Instability Index17
Aromaticity0.1

Similar Structure Search

Candidates based on structure

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