Basic Information
| ID | DRAMP02086 |
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| Sequence | FLPVLTGLTPSIVPKLVCLLTKKC |
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| Length | 24 |
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| Name | Brevinin-1PRa (frogs, amphibians, animals) |
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| Source | Rana pretiosa (North oregon spotted frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.15003829] Gram-negative bacterium: Escherichia coli(MIC>100μM);## Gram-positive bacterium: Staphylococcus aureus(MIC=13μM);## Yeast: Candida albicans(MIC=100μM).[Ref.21295070] Gram-negative bacterium: Escherichia coli(MIC>100μM);## Gram-positive bacterium: Staphylococcus aureus(MIC=50μM);## Yeast: Candida albicans(MIC=100μM). |
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| Hemolytic Activity | [Ref.15003829] HC50=7μM against human erythrocytes.##[Ref.21295070] LC50= 150μM against human erythrocytes. |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys18 and Cys24) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 15003829, 21295070 |
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