Basic Information
| ID | DRAMP02125 |
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| Sequence | IFGAILPLALGALKNLIK |
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| Length | 18 |
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| Name | Hylin-a1 (Hy-a1; Frogs, amphibians, animals) |
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| Source | Hypsiboas albopunctatus (Spotted tree frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.19056441]Gram-positive bacteria: Staphylococcus aureus ATCC 25926 (MIC=8 µM), Enterococcus faecalis ATCC 29212 (MIC=16 µM), Bacillus subtilis ATCC 19659 (MIC=8 µM);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=32 µM), Pseudomonas aeruginosa ATCC 27853 (MIC=64 µM);##Fungi: Candida albicans ATCC 90028 (MIC=16.7 µM), C. krusei ATCC 6258 (MIC=16.7 µM), C. parapsilosis ATCC 22019 (MIC=67 µM), Cryptococcus neoformans ATCC 90012 (MIC=33.5 µM) |
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| Hemolytic Activity | [Ref.19056441]HC50=18 μM against human erythrocytes |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
P85982 |
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| PDB |
2N0O |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 19056441 |
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