Basic Information

IDDRAMP02309
SequenceIIGHLIKTALGFLGL
Length15
NameSigniferin-2.2 (Frogs, amphibians, animals)
SourceCrinia signifera (Common eastern froglet)
ActivityAntimicrobial, Antibacterial, Anti-Gram-
PathogenGram-negative bacteria: Enterobacter cloacae ATCC 13047 (MIC≤100 µM), Escherichia coli ATCC3 5218 (MIC≤100 µM)
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P86132
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15317042, 16470724, 18601958

Physicochemical Properties

Residues15
SequenceIIGHLIKTALGFLGL
Molecular Weight1565.94
Grand Average of Hydropathy1.62
Isoelectric Point8.757
Charge at pH 7.40.592
Secondary StructureHelix: 0.533, Turn: 0.200, Sheet: 0.333
Instability Index3.673
Aromaticity0.067

Similar Structure Search

Candidates based on structure

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