Basic Information

IDDRAMP02353
SequenceRSTEDIIKSISGGGFLNAMNA
Length21
NamePleurocidin-like peptide WFX (fish, chordates, animals; Predicted)
SourcePseudopleuronectes americanus (Winter flounder) (Pleuronectes americanus)
ActivityAntimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Aeromonas salmonicida A449 field isolate (MIC>64 µg/ml), A. salmonicida 97-4 field isolate (MIC>64 µg/ml), Pseudomonas aeruginosa K799 (MIC>64 µg/ml), Pseudomonas aeruginosa Z61 (MIC>64 µg/ml), Escherichia coli (MIC>64 µg/ml), Salmonella typhimurium 14028s (MIC>64 µg/ml), S. typhimurium MS7953s (MIC>64 µg/ml);##Gram-positive bacteria: Staphylococcus epidermidis (human clinical isolates) (MIC>64 µg/ml), Staphylococcus aureus (MRSA) (MIC>64 µg/ml).##Fungi: Candida albica (MIC>64 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot Q7T053
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID12950255

Physicochemical Properties

Residues21
SequenceRSTEDIIKSISGGGFLNAMNA
Molecular Weight2181.426
Grand Average of Hydropathy-0.052
Isoelectric Point6.07
Charge at pH 7.4-0.444
Secondary StructureHelix: 0.238, Turn: 0.381, Sheet: 0.238
Instability Index56.5
Aromaticity0.048

Similar Structure Search

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