Basic Information

IDDRAMP02377
SequenceLFGFLIPLLPHIIGAIPQVIGAIR
Length24
NameGrammistin Gs 2 (Grammistin Gs G; Group I grammistin; soapfish, chordates, animals)
SourceGrammistes sexlineatus (Sixline soapfish) (Golden stripe soapfish)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Bacillus subtilis IAM 1026 (MIC=12.5 µg/ml), Staphylococcus aureus IAM 1011 (MIC=6.25 µg/ml);##Gram-negative bacteria: Aeromonas salmonicida NCIBM 1102 (MIC=50 µg/ml), Escherichia coli JCM 1649 (MIC=50 µg/ml), Photobacterium damselae subsp. Piscicida Sp 9587 (MIC=6.25 µg/ml), Salmonella typhimurium S1 (MIC>50 µg/ml), S. putrefaciens IAM 1509 (MIC=6.25 µg/ml), Vibrio anguillarum NCIBM 829 (MIC=25 µg/ml), Vibrio parahaemolyticus (MIC=25 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P69836
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed IDPubMed ID is not available

Physicochemical Properties

Residues24
SequenceLFGFLIPLLPHIIGAIPQVIGAIR
Molecular Weight2569.179
Grand Average of Hydropathy1.6
Isoelectric Point9.757
Charge at pH 7.40.594
Secondary StructureHelix: 0.542, Turn: 0.250, Sheet: 0.250
Instability Index31.325
Aromaticity0.083

Similar Structure Search

Candidates based on structure

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