Basic Information

IDDRAMP02379
SequenceIGGIISFFKRLF
Length12
NameGrammistin Gs B (Group II grammistin; soapfish, chordates, animals)
SourceGrammistes sexlineatus (Sixline soapfish) (Golden stripe soapfish)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Bacillus subtilis IAM 1026 (MIC=6.25 µg/ml), Staphylococcus aureus IAM 1011 (MIC=6.25 µg/ml);##Gram-negative bacteria: Aeromonas salmonicida NCIBM 1102 (MIC=25 µg/ml), Escherichia coli JCM 1649 (MIC=12.5 µg/ml), P. dameselae subsp. Piscicida Sp 9587 (MIC=6.25 µg/ml), Salmonella typhimurium S1 (MIC=12.5 µg/ml), S. putrefaciens IAM 1509 (MIC=3.13 µg/ml), Vibrio anguillarum NCIBM 829 (MIC=6.25 µg/ml), Vibrio parahaemolyticus (MIC=12.5 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P69839
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15777955

Physicochemical Properties

Residues12
SequenceIGGIISFFKRLF
Molecular Weight1397.705
Grand Average of Hydropathy1.308
Isoelectric Point11.001
Charge at pH 7.41.555
Secondary StructureHelix: 0.583, Turn: 0.250, Sheet: 0.083
Instability Index27.017
Aromaticity0.25

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