Basic Information

IDDRAMP01359
SequenceFLGGLMKIIPAAFCAVTKKC
Length20
NameRanalexin-1G (Frogs, amphibians, animals)
SourceRana grylio (North American pig frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacterium: Escherichia coli (MIC=9 µM);##Gram-positive bacterium: Staphylococcus aureus (MIC=18 µM).##Yeast: Candida albicans (MIC=70 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys14 and Cys20)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10828493

Physicochemical Properties

Residues20
SequenceFLGGLMKIIPAAFCAVTKKC
Molecular Weight2111.678
Grand Average of Hydropathy1.195
Isoelectric Point9.39
Charge at pH 7.42.501
Secondary StructureHelix: 0.350, Turn: 0.150, Sheet: 0.300
Instability Index15.37
Aromaticity0.1

Similar Structure Search

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