Basic Information

IDDRAMP01355
SequenceFLGGLIKIVPAMICAVTKKC
Length20
NameRanalexin (Frogs, amphibians, animals)
SourceLithobates catesbeiana (American bullfrog) (Rana catesbeiana)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacterium: Staphylococcus aureus (MIC=4 µg/ml);##Gram-negative bacteria: Escherichia coli (MIC=32 µg/ml), Pseudomonas aeruginosa (MIC=128 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys14 and Cys20)
Linear/Cyclic/BranchedCyclic
Uniprot P39084
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID8144672, 9578480

Physicochemical Properties

Residues20
SequenceFLGGLIKIVPAMICAVTKKC
Molecular Weight2105.715
Grand Average of Hydropathy1.4
Isoelectric Point9.39
Charge at pH 7.42.501
Secondary StructureHelix: 0.400, Turn: 0.150, Sheet: 0.250
Instability Index17.95
Aromaticity0.05

Similar Structure Search

Candidates based on structure

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