Basic Information

IDDRAMP01951
SequenceFMGGLIKAATKIVPAAYCAITKKC
Length24
NameBrevinin-1PTa (Frogs, amphibians, animals)
SourceRana picturata (Malaysian fire frog) (Hylarana picturata)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=3 µM);##Gram-negative bacterium: Escherichia coli ATCC 25726 (MIC=24 µM).
Hemolytic Activity
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys18 and Cys24)
Linear/Cyclic/BranchedCyclic
Uniprot P0C8T1
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID18621071

Physicochemical Properties

Residues24
SequenceFMGGLIKAATKIVPAAYCAITKKC
Molecular Weight2499.11
Grand Average of Hydropathy0.813
Isoelectric Point9.595
Charge at pH 7.43.496
Secondary StructureHelix: 0.292, Turn: 0.125, Sheet: 0.292
Instability Index20.163
Aromaticity0.083

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.