Basic Information

IDDRAMP01358
SequenceFLGGLFKLVPSVICAVTKKC
Length20
NameRanalexin-Vb (Frogs, amphibians, animals)
SourceRana virgatipes (Ranidae) (Aquarana)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacterium: Escherichia coli (MIC=12 µM);##Gram-positive bacterium: Staphylococcus aureus (MIC=12 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys14 and Cys20)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15996769

Physicochemical Properties

Residues20
SequenceFLGGLFKLVPSVICAVTKKC
Molecular Weight2123.666
Grand Average of Hydropathy1.265
Isoelectric Point9.39
Charge at pH 7.42.501
Secondary StructureHelix: 0.450, Turn: 0.200, Sheet: 0.200
Instability Index18.925
Aromaticity0.1

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.