Basic Information

IDDRAMP01949
SequenceFLPAVLRVAAKIVPTVFCAISKKC
Length24
NameBrevinin-1HSa (Frogs, amphibians, animals)
SourceRana hosii (Hose's rock frog) (Odorrana hosii)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=3 µM);##Gram-negative bacterium: Escherichia coli ATCC 25726 (MIC=24 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys18 and Cys24)
Linear/Cyclic/BranchedCyclic
Uniprot P0C8S7
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID18621071

Physicochemical Properties

Residues24
SequenceFLPAVLRVAAKIVPTVFCAISKKC
Molecular Weight2575.229
Grand Average of Hydropathy1.263
Isoelectric Point9.851
Charge at pH 7.43.501
Secondary StructureHelix: 0.417, Turn: 0.125, Sheet: 0.250
Instability Index34.608
Aromaticity0.083

Similar Structure Search

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