Basic Information

IDDRAMP02009
SequenceFLPVLAGIAAKVVPALFCKITKKC
Length24
NameBrevinin-1 (Frogs, amphibians, animals)
SourceRana brevipoda porsa (Japanese frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.1449472]Gram-positive bacterium: Staphylococcus aureus (MIC=8 µg/ml);##Gram-negative bacterium: Escherichia coli (MIC=34 µg/ml).
Hemolytic Activity[Ref.1449472] high hemolytic activity
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys18 and Cys24)
Linear/Cyclic/BranchedCyclic
Uniprot P32423
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID1449472

Physicochemical Properties

Residues24
SequenceFLPVLAGIAAKVVPALFCKITKKC
Molecular Weight2531.216
Grand Average of Hydropathy1.287
Isoelectric Point9.701
Charge at pH 7.43.498
Secondary StructureHelix: 0.417, Turn: 0.125, Sheet: 0.292
Instability Index31.071
Aromaticity0.083

Similar Structure Search

Candidates based on structure

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