Basic Information

IDDRAMP01950
SequenceFLPAVLRVAAQVVPTVFCAISKKC
Length24
NameBrevinin-1HSb (Brevinin-1JDb; Frogs, amphibians, animals)
SourceRana hosii (Hose's rock frog) (Odorrana hosii)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=3 µM);##Gram-negative bacterium: Escherichia coli ATCC 25726 (MIC>48 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys18 and Cys24)
Linear/Cyclic/BranchedCyclic
Uniprot P0C8S8
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID18621071

Physicochemical Properties

Residues24
SequenceFLPAVLRVAAQVVPTVFCAISKKC
Molecular Weight2561.159
Grand Average of Hydropathy1.267
Isoelectric Point9.504
Charge at pH 7.42.503
Secondary StructureHelix: 0.417, Turn: 0.125, Sheet: 0.250
Instability Index38.542
Aromaticity0.083

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.