Basic Information

IDDRAMP01899
SequenceFLSTLLNVASKVVPTLFCKITKKC
Length24
NameBrevinin-1CG4 (Frogs, amphibians, animals)
SourceAmolops chunganensis (Chungan torrent frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacteria: Rhodococcus rhodochrous X15 (MIC=2.3 µM), Bacillus licheniformis X39 (IS) (MIC=9 µM), Enterococcus faecalis 981 (MIC=9 µM), Staphylococcus carnosus KHS (IS) (MIC=9 µM), Staphylococcus aureus (ATCC 25923) (MIC=9 µM);##Gram-negative bacterium: Escherichia coli (ATCC 25922) (MIC=150 µM), Pseudomonas aeruginosa 11053 (IS) (MIC=75 µM), Psychrobacter faecalis X29 (IS) (MIC=9 µM), Serratia rubidaea X01 (IS) (MIC=9 µM).##Fungi: Slime mold 090223 (IS) (MIC=9 µM), Candida albicans (ATCC 10231) (MIC=150 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22951323

Physicochemical Properties

Residues24
SequenceFLSTLLNVASKVVPTLFCKITKKC
Molecular Weight2654.281
Grand Average of Hydropathy0.846
Isoelectric Point9.701
Charge at pH 7.43.498
Secondary StructureHelix: 0.417, Turn: 0.167, Sheet: 0.208
Instability Index10.533
Aromaticity0.083

Similar Structure Search

Candidates based on structure

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