Basic Information
| ID | DRAMP02075 |
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| Sequence | FLPAVLRVAAKVVPTVFCLISKKC |
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| Length | 24 |
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| Name | Brevinin-1JDc (Frogs, amphibians, animals) |
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| Source | Odorrana jingdongensis (Jingdong frog) (Rana jingdongensis) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.22917879]Gram-positive bacteria: Staphylococcus aureus (MIC=16 µg/ml), S. aureus (MRSA) (MIC=8 µg/ml);##Gram-negative bacterium: Escherichia coli (MIC=128 µg/ml). |
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| Hemolytic Activity | [Ref.22917879] It has 11.7 ± 3.2% hemolytic activity at 64 μg/mL and 88.4 ± 4.2% hemolytic activity at 128 μg/mL against rabbit red blood cells |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys18 and Cys24) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
B3A0N0 |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 22917879 |
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