Basic Information

IDDRAMP01869
SequenceFFPIIAGMAAKLIPSLFCKITKKC
Length24
NameBrevinin-1SPa (Frogs, amphibians, animals)
SourceRana septentrionalis (mink frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.15556063]Gram-negative bacterium: Escherichia coli (MIC=13 µM);##Gram-positive bacterium: Staphylococcus aureus (MIC=6 µM);##Yeast: Candida albicans (MIC=7 µM).
Hemolytic Activity[Ref.15556063]HC50=7 µM against human erythrocytes
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15556063

Physicochemical Properties

Residues24
SequenceFFPIIAGMAAKLIPSLFCKITKKC
Molecular Weight2641.35
Grand Average of Hydropathy1.067
Isoelectric Point9.701
Charge at pH 7.43.498
Secondary StructureHelix: 0.375, Turn: 0.167, Sheet: 0.250
Instability Index22.5
Aromaticity0.125

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