Basic Information

IDDRAMP02944
SequenceYITCLFRGARCRVYSGRSCCFGYYCRRDFPGSIFGTCSRRNF
Length42
NameTachystatin-B2 (crabs, Arthropods, animals)
SourceTachypleus tridentatus (Japanese horseshoe crab)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Antifungal
PathogenGram-positive bacterium: Staphylococcus aureus (IC50=7.4 µg/ml).##Fungi: Candida albicans (IC50=3.0 µg/ml), Pichia pastoris (IC50=0.1 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P0C1Z9
PDB 2DCW
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10473569, 17394123

Physicochemical Properties

Residues42
SequenceYITCLFRGARCRVYSGRSCCFGYYCRRDFPGSIFGTCSRRNF
Molecular Weight4946.68
Grand Average of Hydropathy-0.205
Isoelectric Point9.61
Charge at pH 7.46.401
Secondary StructureHelix: 0.310, Turn: 0.262, Sheet: 0.048
Instability Index59.64
Aromaticity0.214

Similar Structure Search

Candidates based on structure

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