Basic Information

IDDRAMP01055
SequenceAGCIKNGGRCNASAGPPYCCSSYCFQIAGQSYGVCKNR
Length38
NameP. americana AMP (Pa-AMP-1; PAFP-S; Cys-rich; Plant defensin)
SourcePhytolacca americana (American pokeweed) (Phytolacca decandra)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Antifungal
PathogenGram-positive bacteria: Bacillus megaterium (IC50=8 µg/ml), Staphyanococcus sp. (IC50=11 µg/ml).##Fungi: Alternaria panax, Fusarium sp., Rhizoctonia solani.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P81418, O82728
PDB 1DKC
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10759497, 11551192

Physicochemical Properties

Residues38
SequenceAGCIKNGGRCNASAGPPYCCSSYCFQIAGQSYGVCKNR
Molecular Weight3935.454
Grand Average of Hydropathy-0.232
Isoelectric Point8.905
Charge at pH 7.43.448
Secondary StructureHelix: 0.184, Turn: 0.395, Sheet: 0.105
Instability Index26.261
Aromaticity0.105

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