Basic Information

IDDRAMP02945
SequenceDYDWSLRGPPKCATYGQKCRTWSPPNCCWNLRCKAFRCRPR
Length41
NameTachystatin-C (crabs, Arthropods, animals)
SourceTachypleus tridentatus (Japanese horseshoe crab)
ActivityAntimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacterium: Escherichia coli (IC50=1.2 µg/ml);##Gram-positive bacterium: Staphylococcus aureus (IC50=0.8 µg/ml).##Fungi: Candida albicans (IC50=0.9 µg/ml), Pichia pastoris (IC50=0.3 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P0C200
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10473569

Physicochemical Properties

Residues41
SequenceDYDWSLRGPPKCATYGQKCRTWSPPNCCWNLRCKAFRCRPR
Molecular Weight4921.675
Grand Average of Hydropathy-1.08
Isoelectric Point9.549
Charge at pH 7.46.399
Secondary StructureHelix: 0.195, Turn: 0.268, Sheet: 0.098
Instability Index48.173
Aromaticity0.146

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