Basic Information

IDDRAMP02941
SequenceYSRCQLQGFNCVVRSYGLPTIPCCRGLTCRSYFPGSTYGRCQRF
Length44
NameTachystatin-A1 (crabs, Arthropods, animals)
SourceTachypleus tridentatus (Japanese horseshoe crab)
ActivityAntimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacterium: Escherichia coli (IC50=25 µg/ml);##Gram-positive bacterium: Staphylococcus aureus (IC50=4.2 µg/ml).##Fungi: Candida albicans (IC50=3.0 µg/ml), Pichia pastoris (IC50=0.5 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P0C1Z7
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10473569

Physicochemical Properties

Residues44
SequenceYSRCQLQGFNCVVRSYGLPTIPCCRGLTCRSYFPGSTYGRCQRF
Molecular Weight5045.807
Grand Average of Hydropathy-0.241
Isoelectric Point9.378
Charge at pH 7.45.4
Secondary StructureHelix: 0.295, Turn: 0.295, Sheet: 0.068
Instability Index36.334
Aromaticity0.159

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Candidates based on structure

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