Basic Information

IDDRAMP01016
SequenceQCIGNGGRCNENVGPPYCCSGFCLRQPGQGYGYCKNR
Length37
NameAntimicrobial peptide 1 (MJ-AMP1; Plant defensin)
SourceMirabilis jalapa (Garden four-o'clock)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Antifungal
PathogenFungi: Alternaria brassicola (MIC=20 µg/ml), Ascochyta pisi (MIC=200 µg/ml), Botrytis cinerea (MIC=50 µg/ml), Cercospora beticola (MIC=10 µg/ml), Colletotrichum lindemuthianum (MIC=6 µg/ml), Fusarium culmorum (MIC=30 µg/ml), Fusarium oxysporum f.sp.pisi (MIC=15 µg/ml), Fusarium oxysporum f.sp.lycopersici (MIC=200 µg/ml), Nectria haematococca (MIC=15 µg/ml), Phoma betae (MIC=25 µg/ml), Pyrenophora tritici-repentis (MIC=300 µg/ml), Pyricularia oryzae (MIC=6 µg/ml), Rhizoctonia solani (MIC=60 µg/ml), Verticillium dahliae (MIC=12 µg/ml), Venturia inequalis (MIC=12 µg/ml).##Gram-positive bacteria: Bacillus megaterium (MIC=6 µg/ml), Sarcina lutea (MIC=100 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationPyroglutamyl modification (Cyclization of a N-terminal glutamine)
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot P25403
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID1733929, 7647302

Physicochemical Properties

Residues37
SequenceQCIGNGGRCNENVGPPYCCSGFCLRQPGQGYGYCKNR
Molecular Weight4000.487
Grand Average of Hydropathy-0.751
Isoelectric Point8.662
Charge at pH 7.42.401
Secondary StructureHelix: 0.189, Turn: 0.432, Sheet: 0.054
Instability Index21.519
Aromaticity0.108

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