Basic Information

IDDRAMP02959
SequenceRRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFP
Length39
NameAntibacterial protein PR-39 (pigs, mammals, animals)
SourceSus scrofa (Pig)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Escherichia coli K12 D21 (MIC=0.3 µM), Escherichia coli Bd2221175 (MIC=0.3 µM), Salmonella typhimurium LT2 (MIC=1µM), Proteus vulgaris Pvll (MIC=300 µM), Pseudomonas aeruginosa OT97 (MIC=200 µM), Acinetobacter calcoaceticus Acl 1 (MIC=3 µM).##Gram-positive bacteria: Bacillus megaterium (MIC=0.3 µM), Bacillus subtilis (MIC=15 µM), Staphylococcus aureus (MIC=200 µM), Streptococcus pyogenes (MIC=2 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P80054, Q9TR84
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID1765098, 7624374

Physicochemical Properties

Residues39
SequenceRRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFP
Molecular Weight4720.627
Grand Average of Hydropathy-1.308
Isoelectric Point12
Charge at pH 7.49.555
Secondary StructureHelix: 0.231, Turn: 0.513, Sheet: 0.051
Instability Index118.677
Aromaticity0.154

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