Basic Information

IDDRAMP02960
SequenceRIIDLLWRVRRPQKPKFVTVWVR
Length23
NameAntibacterial peptide PMAP-23 (Myeloid antibacterial peptide 23; pigs, mammals, animals)
SourceSus scrofa (Pig)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Escherichia coli ML35 (MIC=2 µM), Escherichia coli ATCC 25922 (MIC=4 µM), Salmonella typhimurium ATCC 14028 (MIC=8 µM), Pseudomonas aeruginosa ATCC 27853 (MIC=16 µM).##Gram-positive bacteria: Bacillus megaterium (MIC=2 µM), Staphylococcus aureus ATCC 25923 (MIC=4 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P49930
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID8132502

Physicochemical Properties

Residues23
SequenceRIIDLLWRVRRPQKPKFVTVWVR
Molecular Weight2962.587
Grand Average of Hydropathy-0.296
Isoelectric Point12
Charge at pH 7.45.553
Secondary StructureHelix: 0.478, Turn: 0.087, Sheet: 0.087
Instability Index50.852
Aromaticity0.13

Similar Structure Search

Candidates based on structure

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