Basic Information

IDDRAMP21303
SequenceRIIDLLARVRRPQKPKFVTVWVR
Length23
NameA7-PMAP-23 (Derived from PMAP-23)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.10527878] Gram-positive bacteria : Bacillus subtilis (KCTC 1918)(MIC=1.56 μM), Streptococcus pyogenes (KCTC 3096)(MIC=1.56 μM), Staphylococcus aureus (KCTC 1621)(MIC=3.125 μM);##Gram-negative bacteria : Escherichia coli (KCTC 1682)(MIC=3.125 μM), Salmonella typhimurium (KCTC 1926)(MIC=1.56 μM), Pseudomonas aeruginosa (KCTC 1637)(MIC=1.56 μM)
Hemolytic Activity[Ref.10527878] 0% hemolysis at 100 μM against human red blood cells
Cytotoxicity[Ref.10527878] No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10527878

Physicochemical Properties

Residues23
SequenceRIIDLLARVRRPQKPKFVTVWVR
Molecular Weight2847.455
Grand Average of Hydropathy-0.178
Isoelectric Point12
Charge at pH 7.45.553
Secondary StructureHelix: 0.435, Turn: 0.087, Sheet: 0.130
Instability Index40.557
Aromaticity0.087

Similar Structure Search

Candidates based on structure

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