Basic Information

IDDRAMP02996
SequenceGNNRPIYIPQPRPPHPRL
Length18
NameApidaecin-2 (Apidaecin II; Insects, animals)
SourceApis mellifera (Honeybee)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Agrobacterium tumefaciens (MIC=0.2 µg/ml), Erwinia salicis (MIC=0.02 µg/ml), Escherichia coli (MIC=0.2 µg/ml), Pseudomonas syringae (MIC=0.1 µg/ml), Rhizobium meliloti (MIC=0.02 µg/ml), Salmonella Newport (MIC=0.2 µg/ml), Salmonella typhimurium (MIC=0.1 µg/ml);##Gram-positive bacteria: Shigella flexneri (MIC=0.1 µg/ml), Corynebacterium insidiosum (MIC=100 µg/ml), Bacillus megaterium (MIC=100 µg/ml)
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot Q06601, P11525, P11526, P11527
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID2676519

Physicochemical Properties

Residues18
SequenceGNNRPIYIPQPRPPHPRL
Molecular Weight2122.435
Grand Average of Hydropathy-1.428
Isoelectric Point11.711
Charge at pH 7.42.591
Secondary StructureHelix: 0.222, Turn: 0.500, Sheet: 0.056
Instability Index46.65
Aromaticity0.056

Similar Structure Search

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