Basic Information
| ID | DRAMP02997 |
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| Sequence | GNNRPVYIPQPRPPHPRL |
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| Length | 18 |
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| Name | Apidaecin-1B (Apidaecin IB; Insects, animals) |
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| Source | Apis mellifera (Honeybee) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.2676519] Gram-negative bacteria: Agrobacterium tumefaciens (MIC=0.2 μg/ml), Erwinia salicis (MIC=0.02 μg/ml), Escherichia coli (MIC=0.1 μg/ml), Pseudomonas syringae (MIC=0.1 μg/ml), Rhizobium meliloti (MIC=0.02 μg/ml), Salmonella Newport (MIC=0.2 μg/ml), Salmonella typhimurium (MIC=0.1 μg/ml), Shigella flexneri (MIC=0.1 μg/ml);##Gram-positive bacteria: Corynebacterium insidiosum (MIC=50 μg/ml), Bacillus megaterium (MIC=100 μg/ml).##[Ref.2298215] Gram-negative bacteria: Agrobacterium tumefaciens Gembloux A (MIC≤1 µg/ml), Erwinia salicis NCPPB 2530 (MIC≤1 µg/ml), Escherichia coli NCTC 9001 (MIC≤1 µg/ml), Escherichia coli K514 (MIC=25-50 µg/ml), Pseudomonas syringae pv.tomato NCPPB 1105 (MIC≤1 µg/ml), Xanthomonas campestris pv. vesicatoria LMG 905 (MIC≥100 µg/ml);##Gram-positive bacteria: Bacillus megateriurn QMB 1551 (MIC=25-50 µg/ml), Bacillus alvei LMG 6922 (MIC=50-100 µg/ml),Micrococcus lysodeikticus LMG 4050 (MIC=25-50 µg/ml). |
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| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
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| Cytotoxicity | [Ref.2298215]No cytotoxicity information found##[Ref.2676519]No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Free |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
P35581, Q06602, Q06601, Q8WSY8 |
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| PDB |
4E81 resolved by X-ray. |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 2676519, 2298215 |
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