| ID | DRAMP03008 |
|---|---|
| Sequence | IKITTMLAKLGKVLAHV |
| Length | 17 |
| Name | Bombolitin I (insects, arthropods, invertebrates, animals) |
| Source | Megabombus pennsylvanicus (Bumblebee) |
| Activity | Antimicrobial, Antibacterial, Anti Mammalian Cells |
| Pathogen | No MICs found in DRAMP database |
| Hemolytic Activity | [Ref.2578459] Hemolysis: ED50=4.0±0.05 µg/ml. Histamine release: ED50=16.3±0.5 µg/ml against guinea pig erythrocytes. |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | P10521 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 2578459 |
Physicochemical Properties
| Residues | 17 |
|---|---|
| Sequence | IKITTMLAKLGKVLAHV |
| Molecular Weight | 1836.332 |
| Grand Average of Hydropathy | 1.035 |
| Isoelectric Point | 10.302 |
| Charge at pH 7.4 | 2.587 |
| Secondary Structure | Helix: 0.412, Turn: 0.059, Sheet: 0.353 |
| Instability Index | -20.553 |
| Aromaticity | 0 |