| ID | DRAMP03009 |
|---|---|
| Sequence | SKITDILAKLGKVLAHV |
| Length | 17 |
| Name | Bombolitin II (insects, arthropods, invertebrates, animals) |
| Source | Megabombus pennsylvanicus (Bumblebee) |
| Activity | Antimicrobial, Antibacterial, Anti Mammalian Cells |
| Pathogen | No MICs found in DRAMP database |
| Hemolytic Activity | [Ref.2578459] Hemolysis: ED50=3.9±0.06 µg/ml. Histamine release: ED50=15.8±0.5 µg/ml against guinea pig erythrocytes. |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | P07493 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 2578459 |
Physicochemical Properties
| Residues | 17 |
|---|---|
| Sequence | SKITDILAKLGKVLAHV |
| Molecular Weight | 1806.197 |
| Grand Average of Hydropathy | 0.712 |
| Isoelectric Point | 9.7 |
| Charge at pH 7.4 | 1.283 |
| Secondary Structure | Helix: 0.412, Turn: 0.118, Sheet: 0.294 |
| Instability Index | -4.229 |
| Aromaticity | 0 |