Basic Information

IDDRAMP03056
SequenceSLLSLIRKLIT
Length11
NameDecoralin (Insects, animals)
SourceOreumenes decoratus (Potter wasp)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.17981364]Gram-positive bacteria: Staphylococcus aureus CCT 6538 (MIC=40 µM), S. saprophyticus (MIC=40 µM), Bacillus subtilis CCT 2471 (MIC=40 µM), B. thuringiensis (MIC=40 µM);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=80 µM), Escherichia coli CCT 1371 (MIC=160 µM), Klebsiella pneumoniae ATCC 13883 (MIC=80 µM), A. faecalis ATCC 8750 (MIC=40 µM);##Fungi: Candida albicans (MIC=40 µM), L. major promastigotes (IC50=72 µM).
Hemolytic Activity[Ref.17981364]EC50=1 mM against mouse erythrocytes
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P85870
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17981364

Physicochemical Properties

Residues11
SequenceSLLSLIRKLIT
Molecular Weight1256.577
Grand Average of Hydropathy1.227
Isoelectric Point11
Charge at pH 7.41.251
Secondary StructureHelix: 0.545, Turn: 0.182, Sheet: 0.364
Instability Index1.373
Aromaticity0

Similar Structure Search

Candidates based on structure

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