Basic Information

IDDRAMP03196
SequenceRCVCRRGVCRCVCTRGFC
Length18
NamePhTD-1 (PhTD1; primates, mammals, animals)
SourcePapio hamadryas (Hamadryas baboon)
ActivityAntimicrobial, Antibacterial, Antifungal
PathogenIn low salt conditions: Escherichia coli ML35p (MIC=1.5 µM), Listeria monocytogenes EGD (MIC=1.6 µM) and methicillin-resistant Staphylococcus aureus ATCC 33591 (MIC=2.5 µM),.##Fungi: Candida albicans 820 (MIC=1.6 µM);##At high physiological salt concentrations: Escherichia coli ML35p (MIC=2.0 µM), Listeria monocytogenes EGD (MIC=1.7 µM), Staphylococcus aureus ATCC 33591 (MIC=3.6 µM), Candida albicans 820 (MIC=6.5 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationNo specific N-terminal
C-terminal ModificationNo specific C-terminal
Linear/Cyclic/BranchedCyclic
Uniprot P86722, P86723
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID20155756

Physicochemical Properties

Residues18
SequenceRCVCRRGVCRCVCTRGFC
Molecular Weight2077.575
Grand Average of Hydropathy0.356
Isoelectric Point9.303
Charge at pH 7.44.41
Secondary StructureHelix: 0.222, Turn: 0.111, Sheet: 0.000
Instability Index41.567
Aromaticity0.056

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