Basic Information

IDDRAMP03331
SequenceLRDLVCYCRKRGCKRRERMNGTCRKGHLMYTLCCR
Length35
NameAlpha-defensin cryptdin-3 (Defensin-related cryptdin-3; Rodents, mammals, animals)
SourceMus musculus (Mouse)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Listeria monocytogenes EGD;##Gram-negative bacteria: Escherichia coli ML-35p, mouse-avirulent Salmonella typhimurium 7953.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot P28310, Q499K7
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID1500431

Physicochemical Properties

Residues35
SequenceLRDLVCYCRKRGCKRRERMNGTCRKGHLMYTLCCR
Molecular Weight4280.18
Grand Average of Hydropathy-0.811
Isoelectric Point9.993
Charge at pH 7.48.436
Secondary StructureHelix: 0.200, Turn: 0.114, Sheet: 0.200
Instability Index42.98
Aromaticity0.057

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